The BRAF antibody has two options including the mouse monoclonal version and the rat monoclonal version. Either one is designed to be used for research. Both versions are a member of the RAF family. They both focus on mitogenic signals to the nucleus from the cell membrane. Mutations are highly common in malignant and benign human tumors, such as papillary thyroid carcinoma, melanoma, colorectal carcinoma and ovarian cancer.
The mouse BRAF antibody has a clone called VE1, and the immunogen is the synthetic peptide that represents the B-FRAF V600E mutated amino acid sequence. The isotype is the Mouse IgG2a, and it has an undetermined epitope. The molecular weight is 95 kDa, and it is designed to be used with immunohistochemistry applications. The positive control is the colon carcinoma with a BRAF V600E mutation with cellular localization occurring in the cytoplasm. You will find three purchase options including 0.1, 0.5, and 1.0 ml. All are purified by the protein A/G in a Tris buffer with a pH of 7.5 and a 0.3% carrier protein with less than 0.1% of sodium azide.
The Rat BRAF antibody has a clone called pBR1, and the immunogen is the full-length recombinant human protein. The isotype is the Rat IgG2a and has an undetermined epitope. The molecular weight is 95 kDa, and it is suitable for Immunohistochemistry and Western Blotting applications. The positive control is the colon carcinoma, and the cellular localization is in the cytoplasm. While Western Blotting is possible, it is recommended but untested. This version comes in four purchase options, including a pre-diluted version only appropriate for IHC applications. The others come in 0.1, 0.5, and 1.0 ml versions in a PBS/1% buffer with a pH of 7.6.
The BRAF antibody can be used for a variety of research needs. Visit Spring Bioscience now to learn more.
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